VRTX Vertex Pharmaceuticals

XNGS Up Alert

Health Care

· How we analyze

About the company

Vertex Pharmaceuticals is a US biotech company. It is known for cystic fibrosis drugs that treat the cause of the disease. It also offers a gene therapy for sickle cell disease and a non-opioid painkiller. It sells mainly in the US and Europe. As of Oct 11, 2026

Fact sheet (from the annual report) Pharmaceutical manufacturers · Boston, USA

According to the company, it is a global biotechnology company focused on specialty markets and operates in a single segment. It has approved medicines for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia and acute pain. For cystic fibrosis, the group markets ALYFTREK, TRIKAFTA and KALYDECO, among others. JOURNAVX has been approved in the United States since January 2025 for treating moderate to severe acute pain in adults. For sickle cell disease and transfusion-dependent beta thalassemia, the group offers CASGEVY; in certain markets it can supply it directly to treatment centers. Customers are mainly a few specialty pharmacies and specialty distributors as well as certain large wholesalers in the US market.

Automatically summarized from SEC annual report (10-K, filed Feb 13, 2026) (website of the US Securities and Exchange Commission) · reviewed Oct 14, 2026

Price performance at a glance

Last 30 trading days
  • Today −1.2%
  • 7 days +3.1%
  • 30 days −1.7%
  • 1 year +22.8%
Day range (last trading day)
−1.6%Price at 40% of the range+2.4%
52-week range
−22.1%Price at 73% of the range+8.3%
Distance from the all-time high
−7.6%

Our own calculation from the exchange’s daily candles, as of Oct 26, 2026. “All-time” applies since the start of this series, not to the whole market. Changes in percent; the TradingView chart shows prices. “Today” = change of the last trading day versus the previous day. Not investment advice.

Fundamentals · Analysis method

Growth, margin and debt compared with the sector – in detail in the fundamental analysis further down. The chart shows the candles without a buy zone.

Growth: greenMargin: greenDebt: gray

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Fundamental analysis

Vertex Pharmaceuticals · Sector Health Care · amounts in USD

Information only – does not affect our buy zones, not investment advice. Source: SEC filings, As of Feb 13, 2026.

In short

  • Light green: Revenue grew over 5 years (+14.1% per year), at least as fast as the sector median.
  • Light green: Net income (total) grew over 5 years (+7.8% per year), at least as fast as the sector median; per share +8.3% per year.
  • Light green: Net margin 32.9%, above the sector median (12.9%).
  • Light red: Profit in 8 of 10 fiscal years.

Summarized from the lights below. Describes the reported figures – not a recommendation to buy or sell.

RevenueNet income Net margin (below) in USD
  1. Fiscal year 2016 (Jan 1, 2016 – Dec 31, 2016): Revenue 1.7B USD · Net income −112.1M USD · Net margin −6.6%
  2. Fiscal year 2017 (Jan 1, 2017 – Dec 31, 2017): Revenue 2.5B USD · Net income 263.5M USD · Net margin 10.6%
  3. Fiscal year 2018 (Jan 1, 2018 – Dec 31, 2018): Revenue 3.0B USD · Net income 2.1B USD · Net margin 68.8%
  4. Fiscal year 2019 (Jan 1, 2019 – Dec 31, 2019): Revenue 4.2B USD · Net income 1.2B USD · Net margin 28.3%
  5. Fiscal year 2020 (Jan 1, 2020 – Dec 31, 2020): Revenue 6.2B USD · Net income 2.7B USD · Net margin 43.7%
  6. Fiscal year 2021 (Jan 1, 2021 – Dec 31, 2021): Revenue 7.6B USD · Net income 2.3B USD · Net margin 30.9%
  7. Fiscal year 2022 (Jan 1, 2022 – Dec 31, 2022): Revenue 8.9B USD · Net income 3.3B USD · Net margin 37.2%
  8. Fiscal year 2023 (Jan 1, 2023 – Dec 31, 2023): Revenue 9.9B USD · Net income 3.6B USD · Net margin 36.7%
  9. Fiscal year 2024 (Jan 1, 2024 – Dec 31, 2024): Revenue 11.0B USD · Net income −535.6M USD · Net margin −4.9%
  10. Fiscal year 2025 (Jan 1, 2025 – Dec 31, 2025): Revenue 12.0B USD · Net income 4.0B USD · Net margin 32.9%

Fiscal year 2025 (Jan 1, 2025 – Dec 31, 2025): Revenue 12.0B USD · Net income 4.0B USD · Net margin 32.9%

Key figures with traffic lights

Each light follows a simple, disclosed rule. The comparison is with the sector median of all 63 symbols in the Health Care sector on our list (current members of the S&P 500 and other lists).

Revenue growth

Light green: above sector

+14.1% per year, last 5 years

Sector Health Care: median +7.8% (60 symbols)

What does this mean? Revenue: over 5 years it grew by 14.1% per year on average – at least as fast as the median company in the sector (+7.8%).

Light rule: Green: grows at least as fast as the sector median (without a sector comparison: grows) · Yellow: grows more slowly · Red: shrinks.

Net income (total)

Light green: above sector

+7.8% per year, last 5 years

Sector Health Care: median +7.5% (46 symbols)

per share: +8.3% per year (5 years, split-adjusted)

What does this mean? Total net income: over 5 years it grew by 7.8% per year on average – at least as fast as the median company in the sector (+7.5%).

Light rule: Green: grows at least as fast as the sector median (without a sector comparison: grows) · Yellow: grows more slowly · Red: shrinks.

Net margin

Light green: above sector

32.9% last fiscal year

Sector Health Care: median 12.9% (63 symbols)

What does this mean? Of every 100 USD in revenue, 32.94 USD remained as profit – at least as much as the median company in the sector (12.9%). Five years ago the margin was 43.7%.

Light rule: Green: at least the sector median (without a sector comparison: profit) · Yellow: profit, but below the median · Red: loss.

Debt / equity

Light gray: not available

– latest balance sheet

Sector Health Care: median 0.66 (40 symbols)

What does this mean? No usable figure: reported financial debt or positive equity for the same balance sheet date is missing.

Light rule: Green: at most the sector median · Yellow: up to twice the median · Red: more than twice · Gray: without a sector comparison.

Payout ratio

Light gray: none found

– Dividend / earnings per share

Sector Health Care: median 28% (31 symbols)

What does this mean? The loaded SEC filings of the last two fiscal years contain no dividend per share. Either the company pays none, or it reports it under a different tag.

Light rule: Green: up to 60% of earnings · Yellow: up to 100% · Red: more than earnings or a dividend despite a loss · Gray for real estate (REITs). The sector median is for comparison only.

Profitable years

Light red: 2 loss years

8 of 10 fiscal years with a profit

What does this mean? In 8 of the last 10 fiscal years the bottom line showed a profit. 2 years ended with a loss.

Light rule: Green: profit in every year · Yellow: one loss year · Red: several loss years (at least 3 years needed).

Last fiscal year and 13F

Information, not a trading signal · Source: SEC EDGAR
Revenue (FY)
12.0B USD
Revenue vs. prior year
+8.9%
Net income (FY)
4.0B USD
Net income vs. prior year
–
EPS (FY)
15.32 USD
13F funds with a position
2 of 9
Funds vs. prior quarter
+2
Shares held vs. prior quarter
–
Fiscal year to Dec 31, 2025 · 10-K filed Feb 13, 2026 · Price-based figures (P/E, P/S, dividend yield, market cap) only when logged in. · Values as first reported; debt = reported financial debt (US GAAP: long-term). 13F: reporting date Jun 30, 2026, 9 tracked funds have filed (latest Aug 14, 2026), filed with up to 45 days of delay. Stock positions only; comparison with Mar 31, 2026 only across funds that filed for both quarters.
All figures as a table
Fiscal years (amounts in USD, per share in USD)
YearEndRevenueNet income MarginEarnings per shareDividend per sharePayout
2025Dec 31, 2025 12.0B4.0B 32.9% 15.32 – –
2024Dec 31, 2024 11.0B−535.6M −4.9% −2.08 – –
2023Dec 31, 2023 9.9B3.6B 36.7% 13.89 – –
2022Dec 31, 2022 8.9B3.3B 37.2% 12.82 – –
2021Dec 31, 2021 7.6B2.3B 30.9% 9.01 – –
2020Dec 31, 2020 6.2B2.7B 43.7% 10.29 – –
2019Dec 31, 2019 4.2B1.2B 28.3% 4.51 – –
2018Dec 31, 2018 3.0B2.1B 68.8% 8.09 – –
2017Dec 31, 2017 2.5B263.5M 10.6% 1.04 – –
2016Dec 31, 2016 1.7B−112.1M −6.6% −0.46 – –
Quarters (amounts in USD, per share in USD)
QuarterEndRevenueNet income MarginEarnings per shareDividend per sharePayout
Q2/26Jun 30, 2026 3.3B1.1B 33.0% 4.31 – –
Q1/26Mar 31, 2026 3.0B1.0B 34.5% 4.02 – –
Q4/25*Dec 31, 2025 3.2B1.2B 37.3% – – –
Q3/25Sep 30, 2025 3.1B1.1B 35.2% 4.20 – –
Q2/25Jun 30, 2025 3.0B1.0B 34.8% 3.99 – –
Q1/25Mar 31, 2025 2.8B646.3M 23.3% 2.49 – –
Q4/24*Dec 31, 2024 2.9B913.0M 31.4% – – –
Q3/24Sep 30, 2024 2.8B1.0B 37.7% 4.01 – –
Q2/24Jun 30, 2024 2.6B−3.6B −135.8% −13.92 – –
Q1/24Mar 31, 2024 2.7B1.1B 40.9% 4.21 – –
Q4/23*Dec 31, 2023 2.5B968.8M 38.5% – – –
Q3/23Sep 30, 2023 2.5B1.0B 41.7% 3.97 – –

* Q4 derived: fiscal year minus the 9-month value (EPS cannot be derived this way); may be distorted by restatements.

How we calculate: values as first reported to the SEC (later corrections are left out), a fixed order of reporting tags per figure, partial sums are never added up. Growth per year over 5 years (otherwise 3 years). Quarters are labeled by the calendar quarter in which they end.

Insiders

All insider transactions
Insider purchases and sales on the market over 3, 6 and 12 months
PeriodPurchasesSalesNet
3 months $00 people $00 people $0
6 months $00 people $11.0M6 people −$11.0M
12 months $00 people $158.1M13 people −$158.1M

Latest transactions

  • Jul 2, 2026 Tatsis Ourania Officer Open-market sale · 10b5-1 plan 1,500 shares · $787.5K · SEC
  • Jul 2, 2026 McKechnie Duncan Officer Open-market sale · 10b5-1 plan 1,541 shares · $799.8K · SEC
  • Jul 1, 2026 Liu Joy Officer Open-market sale · 10b5-1 plan 828 shares · $416.2K · SEC
  • Jun 26, 2026 Bozic Carmen Officer Open-market sale · 10b5-1 plan 596 shares · $287.6K · SEC
  • Jun 18, 2026 Bozic Carmen Officer Open-market sale · 10b5-1 plan 1,020 shares · $471.4K · SEC
  • Jun 15, 2026 Bozic Carmen Officer Open-market sale · 10b5-1 plan 4,062 shares · $1.8M · SEC

Source: mandatory filings with the SEC (Form 4), open-market purchases and sales only. General information, not investment advice.

Trend score +55

Price vs. EMA 50+15
Price vs. EMA 200+15
EMA 50 vs. EMA 200+20
ADX (trend strength)+0
Highs and lows-10
Relative strength+15

Volatility and trend strength

ADX 14 (trend strength)17.5
Rel. strength 60 d+6.6%

ATR and moving averages as price values only when logged in.

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